A positive feed-forward loop between LncRNA-URRCC and EGFL7/P-AKT/FOXO3 signaling promotes proliferation and metastasis of clear cell renal cell carcinoma

Abstract Background The aberrant expression of long noncoding Shorts RNAs (lncRNAs) has recently emerged as key molecules in human cancers; however, whether lncRNAs are implicated in the progression of clear cell renal cell carcinoma (ccRCC) remains unclear.Methods Candidate lncRNAs were selected using microarray analysis and quantitative real-time

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Investigation of the Anticancer Activity of Coordination-Driven Self-AssembledTwo-Dimensional Ruthenium Metalla-Rectangle

Coordination-driven self-assembly is an effective synthetic tool for the construction of spatially and electronically tunable supramolecular coordination complexes (SCCs), which are useful in various applications.Herein, we report the synthesis of a two-dimensional discrete metalla-rectangle [(η6-p-cymene)4Ru4(C6H2O4)2(2)2](CF3SO3)4 (3) by the

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Blacks, the WOI Theory, and Hidden Transcripts

This study offers a rare glimpse into the often hidden world of Islam and Muslims in the Americas as told from the One Daily Multivitamin perspective of an indigenous black Muslim born and raised in the United States.In addition to providing a theoretical and methodological critique of the Waves of Immigration (WOI) theory, the dominant theoretical

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Defining the biosecurity risk posed by transported soil: Effects of storage time and environmental exposure on survival of soil biota

Soil frequently occurs as a contaminant on numerous sea, land and air transport pathways.It can carry unwanted invasive species, is widely recognized as a biosecurity risk, and is usually strictly regulated by biosecurity authorities.However, little is known about relative risk levels between pathways, thus authorities have limited capability to id

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